Nsalu zatsopano zogwiritsiridwanso ntchito zimatha kuthetsa kuopseza kwachilengedwe ndi mankhwala

Nsalu yopangidwa ndi siponji yopangidwa ndi crystalline yomwe ingagwiritsidwe ntchito kuthetsa ziwopsezo zachilengedwe ndi mankhwala.Chithunzi chojambula: Northwestern University
Zinthu zambiri zopangidwa ndi fiber zochokera ku MOF zomwe zidapangidwa pano zitha kugwiritsidwa ntchito ngati nsalu yoteteza ku zoopsa zachilengedwe ndi mankhwala.
Nsalu zokhala ndi ntchito zambiri komanso zongowonjezwdwa za N-chloro-based insecticidal ndi detoxifying nsalu zimagwiritsa ntchito zirconium metal organic frame (MOF)
Fiber composite material imasonyeza mofulumira biocidal zochita motsutsana ndi mabakiteriya a Gram-negative (E. coli) ndi Gram-positive bacteria (Staphylococcus aureus), ndipo mtundu uliwonse ukhoza kuchepetsedwa mpaka 7 logarithms mkati mwa mphindi 5.
MOF/fiber composites yodzaza ndi klorini yogwira imatha kuwononga mpiru wa sulfure mwachangu komanso analogue yake yamankhwala 2-chloroethyl ethyl sulfide (CEES) yokhala ndi theka la moyo wosakwana mphindi zitatu.
Gulu lofufuza kuchokera ku yunivesite ya Northwestern University lapanga nsalu zophatikizika zambiri zomwe zimatha kuthetsa ziwopsezo zamoyo (monga coronavirus yatsopano yomwe imayambitsa COVID-19) ndi ziwopsezo zamankhwala (monga zomwe zimagwiritsidwa ntchito pankhondo yamankhwala).
Nsaluyo itawopsezedwa, zinthuzo zikhoza kubwezeretsedwanso ku chikhalidwe chake choyambirira pogwiritsa ntchito mankhwala ophweka a blekning.
"Kukhala ndi zinthu ziwiri zomwe zimagwira ntchito nthawi imodzi zomwe zimatha kuyambitsa poizoni wamankhwala ndi zachilengedwe ndizofunikira kwambiri chifukwa zovuta zophatikiza zida zingapo kuti amalize ntchitoyi ndizokwera kwambiri," adatero Omar Farha waku Northwestern University, yemwe ndi chitsulo-organic chimango kapena akatswiri a MOF. , awa ndiye maziko aukadaulo.
Farha ndi pulofesa wa chemistry pa Weinberg School of Arts and Sciences komanso wolemba mnzake wa kafukufukuyu.Ndi membala wa International Institute of Nanotechnology ku Northwestern University.
Ma composites a MOF/fiber adatengera kafukufuku wam'mbuyomu pomwe gulu la Farha lidapanga nanomaterial yomwe imatha kuyambitsa poizoni wa mitsempha.Kupyolera mu maopaleshoni ang'onoang'ono, ofufuza amathanso kuwonjezera ma antiviral ndi antibacterial agents kuzinthuzo.
Faha adanena kuti MOF ndi "siponji yosambira yolondola."Zida zazikulu za nano zimapangidwa ndi mabowo ambiri, omwe amatha kutsekera mpweya, nthunzi ndi zinthu zina monga siponji imatchera madzi.Mu nsalu yatsopano yophatikizika, patsekeke ya MOF ili ndi chothandizira chomwe chimatha kuyambitsa mankhwala oopsa, ma virus ndi mabakiteriya.Porous nanomaterials mosavuta TACHIMATA pa nsalu ulusi.
Ofufuza adapeza kuti ma composites a MOF/fiber adawonetsa kuchitapo kanthu mwachangu motsutsana ndi SARS-CoV-2, komanso mabakiteriya a Gram-negative (E. coli) ndi mabakiteriya a Gram-positive (Staphylococcus aureus).Kuphatikiza apo, ma composites a MOF/fiber odzaza ndi chlorine yogwira amatha kuwononga mwachangu mpweya wa mpiru ndi ma analogue ake amankhwala (2-chloroethyl ethyl sulfide, CEES).Ma nanopores a zinthu za MOF zokutidwa pansalu ndizazikulu mokwanira kulola kuti thukuta ndi madzi zituluke.
Farha adawonjezeranso kuti zinthu zophatikizikazi ndizowopsa chifukwa zimangofunika zida zopangira nsalu zomwe zimagwiritsidwa ntchito pamakampani pano.Akagwiritsidwa ntchito limodzi ndi chigoba, zinthuzo ziyenera kugwira ntchito nthawi imodzi: kuteteza wovala chigoba ku ma virus omwe ali pafupi ndi iwo, komanso kuteteza anthu omwe akumana ndi munthu yemwe ali ndi kachilomboka atavala chigobacho.
Ofufuza atha kumvetsetsanso malo omwe akugwira ntchito pamlingo wa atomiki.Izi zimawalola iwo ndi ena kupeza maubwenzi ogwirizana kuti apange zinthu zina zamagulu a MOF.
Sungunulani chlorine yongowonjezwdwa yokhazikika mu zirconium zochokera ku MOF zophatikizika za nsalu kuti muchotse ziwopsezo zachilengedwe ndi zamankhwala.Journal ya American Chemical Society, Seputembara 30, 2021.
Mtundu wa Gulu Gulu Mtundu Wagulu/Makampani Ophunzirira Boma la Boma la Boma/Maboma Ang'ono Asilikali Opanda Phindu a Media/Ubale Wagulu Zina